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What is Irido Corneal Endothelial Syndrome (ICE)?

ICE is a rare form of glaucoma which usually is found in only one eye.

In this condition, cells on the back surface of the cornea spread over the eye’s drainage tissue and across the surface of the iris. This causes an increase in eye pressure, which can damage the optic nerve. These cells also form adhesions that bind the iris to the cornea, further blocking the drainage channels.

ICE occurs more frequently in light-skinned females. Symptoms can include hazy vision upon awakening and the appearance of halos around lights. ICE is difficult to treat and laser therapy is not an effective therapy. ICE is usually treated with medications and/or filtering surgery.

Last reviewed on August 23, 2012

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